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The relationship between methylation and stomach acid secretion
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James Offline
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The relationship between methylation and stomach acid secretion
Do you have any knowledge on the relationship between methylation and stomach acid secretion?

Methylation of phospholipids is involved in the production of phosphatidylcholine , leading to the production of the neurotransmitter acetylcholine. Acetylcholine, gastrin and histamine are required for the release of stomach acid. Methylation decreases with age, which can explain the drop in stomach acid levels as we age.

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07-27-2012 05:22 AM
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James Offline
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RE: The relationship between methylation and stomach acid secretion
Can one supplement with L-histidine and possibly niacin to induce gastric acid secretion?

I would not recommend it. Increasing histamine can have side effects and excess niacin requires methylation to process thereby using up available methyl groups, which decreases methylation in the long run.

http://www.MountainMistBotanicals.com
07-27-2012 05:23 AM
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Brigid Offline
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RE: The relationship between methylation and stomach acid secretion
if one has inherited an aberration of the MTHFR gene and methylation is abnormal, can this be corrected, or what's the best way to 'cope' with this as a lifelong condition?
08-29-2012 10:47 PM
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James Offline
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RE: The relationship between methylation and stomach acid secretion
(08-29-2012 10:47 PM)Brigid Wrote:  if one has inherited an aberration of the MTHFR gene and methylation is abnormal, can this be corrected, or what's the best way to 'cope' with this as a lifelong condition?

You cannot really correct genetic disorders, only address the symptoms. In such a case I would recommend supplementing with trimethylglycine (TMG) to provide methyl groups for methylation.

http://www.MountainMistBotanicals.com
09-03-2012 03:08 AM
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