MedCapsules Forum
The Chemistry of Ozone Therapy on Cancer - Printable Version

+- MedCapsules Forum (http://medcapsules.com/forum)
+-- Forum: Main Lobby (/forumdisplay.php?fid=1)
+--- Forum: Holistic Medical Topics (/forumdisplay.php?fid=18)
+---- Forum: Cancer (/forumdisplay.php?fid=12)
+----- Forum: Alternative Therapies for Cancer (/forumdisplay.php?fid=83)
+------ Forum: Oxygen Therapies (/forumdisplay.php?fid=89)
+------ Thread: The Chemistry of Ozone Therapy on Cancer (/showthread.php?tid=24455)



The Chemistry of Ozone Therapy on Cancer - James - 04-14-2015 11:24 PM

Ozone therapy is the safest and most effective cancer therapy I have ever found.

An interesting aspect of ozone therapy is that ozone has the ability to selectively destroy cancer cells without damaging healthy tissue.
See: http://www.ncbi.nlm.nih.gov/pubmed/7403859

Science. 1980 Aug 22;209(4459):931-3.

Ozone selectively inhibits growth of human cancer cells.
Sweet F, Kao MS, Lee SC, Hagar WL, Sweet WE.

Abstract

The growth of human cancer cells from lung, breast, and uterine tumors was selectively inhibited in a dose-dependent manner by ozone at 0.3 to 0.8 part per million of ozone in ambient air during 8 days of culture. Human lung diploid fibroblasts served as noncancerous control cells. The presence of ozone at 0.3 to 0.5 part per million inhibited cancer cell growth 40 and 60 percent, respectively. The noncancerous lung cells were unaffected at these levels. Exposure to ozone at 0.8 part per million inhibited cancer cell growth more than 90 percent and control cell growth less than 50 percent. Evidently, the mechanisms for defense against ozone damage are impaired in human cancer cells.

Another interesting aspect of ozone when dealing with cancer is that the ozone fights cancer through a variety of mechanisms. Some of the anticancer effects of ozone include:

-Destruction of cancer producing pathogens.

-Oxidative destruction of xenoestrogens and other carcinogens.

-Increasing levels of immune stimulating and cancer fighting cytokines.

-Increasing levels of superoxide dismutase (SOD). SOD converts the superoxide anion in to oxygen, and anti-cancer and immune stimulating hydrogen peroxide.

-Increasing white blood cell activity.

-Decreasing lactate levels preventing its conversion back in to glucose through gluconeogenesis.

-Immediate and direct destruction of cancer cells through an overload of peroxide within the cancerous cells.


Advantages of ozone over allopathic treatments include:

-Cancerous cells cannot build up a tolerance to ozone the way it can to chemotherapy or radiation therapy. This is especially useful for destroying metastasized cells that can migrate in to the brain or bone where they are hard to treat with allopathic methods.

-Ozone therapy is not inhibited by a poor vasculature within tumors as is the case with chemotherapy and radiation therapy, which is why most of these therapies have such low success rates. Studies have shown that the combination of ozone therapy with chemotherapy increases the effectiveness of the chemotherapy drugs by increasing oxygen levels and thus oxygen radicals within the hypoxic regions of tumors. The same would apply to ozone being used in conjunction with radiation therapy since radiation therapy is also limited in success due to a lack of oxygen radical formation within the hypoxic regions of the tumor.

-Ozone therapy does not cause metastases of cancer cells like biopsies and radiation therapy can.

-Ozone therapy is not carcinogenic (cancer causing) or immune suppressing like radiation therapy and chemotherapy.

-Ozone stimulates the healing of damaged tissues in low concentrations.

-Ozone treatments can be self administered at home.

-Ozone therapy is cost efficient. Cold corona units needed for therapy can be purchased for between $500-1500, with an additional $200 for an oxygen tank and regulator. The cost of oxygen and electricity averages less than $0.10 per treatment.

-Properly administered ozone therapy has an extremely high safety rate. In one study conducted in Germany following the application of over 6.5 million doses of ozone given there were slightly over 30 adverse reactions. Most of these due to improper administration and were often mild such as minor irritation at the injection site.

-Ozone therapy increases the levels of antioxidant enzymes so that oxidative damage to healthy cells is minimal to non-existent when ozone is used properly.

To understand how ozone selectively destroys cancer cells we first need to go over some basic chemistry. Ozone is generally accepted as being O3, although higher allotropes (O4 and up) do exist. If I write up the formula this way O:O·O we can see that two of the oxygen atoms are stable due to paired electrons, but the third oxygen atom is not. This makes the ozone molecule itself unstable and reactive. As the ozone molecule is broken down singlet oxygen (O1 or O·) is formed. Singlet oxygen is one of the strongest oxidizers known, with only fluorine exceeding it in oxidation power.

The oxygen we breath, O2, is stable because it has paired balancing electrons (O:O). Singlet oxygen (O·) on the other hand does not have a paired electron to stabilize it. This makes the singlet oxygen highly reactive since it is needs to seek out an electron it can steal to stabilize itself. For example, as ozone breaks down the singlet oxygen atoms released can react with each other to form a more stable O2.

Other sources for singlet oxygen to obtain electrons from to stabilize can include carcinogens, cancer microbes, water and lipids (fats). It is this reactivity that allows ozone to have so many anticancer properties.

These anticancer properties include:

-Killing cancer pathogens by either reacting with the lipids in the membranes of the pathogen creating lipid peroxides destroying the pathogen directly, or by reacting with water to form hydrogen peroxide that in turn destroys the pathogen.

-Destruction of carcinogens, such as xenoestrogens through oxidative destruction by ozone.

-Peroxides formed by ozone increase production of immune supporting cytokines.

-Peroxides created by the reaction of ozone on water lead to cellular apoptosis (self destruction) of low adenosine triphosphate (ATP) containing cells such as aged cells and cancerous tumor cells.

-Both lipid peroxides and hydrogen peroxide created during ozone therapy increase white blood activity, which are a primary component of the immune system.

-The formation of lipid and hydrogen peroxides lead to the selective destruction of cancerous tumor cells through an overload of peroxide within the cells.

Before I go any further though, I also need to point out a key difference between cancerous tumor cells and healthy cells. This will help further explain how ozone selectively kills cancer cells.

Peroxides are generated by our own cells because peroxide is required for a number of functions within the body. These functions include destruction of pathogens, activation of white blood cells, stimulating production of immune enhancing cytokines and destruction of cancerous cells by natural killer (NK) cells.

Peroxide can also damage cells. Therefore, healthy cells contain antioxidant enzymes known as catalase (CAT) and other peroxidases, such as the glutathione peroxidases. These enzymes break down peroxides protecting healthy cells from oxidative damage by these peroxides.

Cancer cells contain significantly lower levels of these antioxidant enzymes. Therefore, cancer cells are not able to deal with an influx of peroxide. Since the peroxides entering the cancer cells are not being enzymatically broken down in to harmless water and oxygen the influx of peroxide in to the cancer cells cause the cancer cells to swell and burst.

This is the same mechanism by which cancer cells are destroyed by the immune system when they can be detected by the immune system. Cancerous cells are often hard for the immune system to detect since they can “shield” themselves from the immune system to avoid detection. When the immune system does detect cancerous tumor cells NK cells attach to the detected cancer cells. Once attached the NK cells inject peroxide in to the cancer cells causing the cancer cells to swell and burst. This is an Achilles’ heel for cancerous cells. Because cancerous cells are deficient in antioxidant enzymes they cannot break down peroxides efficiently like healthy cells. Therefore, peroxide entering the cancer cells will swell cancer cells to the point of rupturing.

Ozone has a very similar effect on cancer cells as NK cells. When ozone reacts with the lipids (fats) of cancer cell membranes lipid peroxides are formed. Singlet oxygen formed from the breakdown of ozone will also form some hydrogen peroxide by reaction with extracellular water. These peroxides enter cancer cells causing the cancer cells to swell until they burst. During the process more singlet oxygen is generated, which in turn creates more peroxides leading to a chain reaction. Therefore, very small amounts of ozone are capable of destroying extensive amounts of cancer cells upon contact.

Healthy cells are not damaged since they contain sufficient levels of antioxidant enzymes to deal with the influx of peroxides. Ozone therapy further increases levels of these antioxidant enzymes in healthy cells.

One study performed in Germany found that when ozone was injected in to mammary carcinomas of mice that the tumors were completely destroyed within 5 minutes of injection. There was no damage to surrounding healthy tissue.

Ozone therapy must be properly administrated with the proper dosage for the therapy to be safe and effective. Therefore, ozone therapy should not be applied without proper knowledge and training.


RE: The Chemistry of Ozone Therapy on Cancer - Anderson - 04-15-2015 01:55 AM

"Peroxide can also damage cells. Thereofore, healthy cells contain antioxidant enzymes known as catalase (CAT) and peroxidases, such as the glutathione peroxidases. These enzymes break down peroxides protecting healthy cells from oxidative damage by these peroxides. "

What if one has glutathione deficiency? Would it still be safe?


RE: The Chemistry of Ozone Therapy on Cancer - James - 04-15-2015 07:46 PM

(04-15-2015 01:55 AM)Anderson Wrote:  "Peroxide can also damage cells. Thereofore, healthy cells contain antioxidant enzymes known as catalase (CAT) and peroxidases, such as the glutathione peroxidases. These enzymes break down peroxides protecting healthy cells from oxidative damage by these peroxides. "

What if one has glutathione deficiency? Would it still be safe?

Glutathione forms glutathione peroxidase. Contrary to the sales hype it is not the only nor the primary antioxidant for the body. The body produces 8 peroxidase enzymes and still utilizes various other antioxidants such as uric acid and some vitamins.

In addition, ozone therapy increases levels of these antioxidant enzymes.

So the short answer is yes. But it still must be used properly, which includes low concentrations internally to prevent damage and overwhelming the antioxidant system.